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NEUROLOGY 1976;26:699
© 1976 American Academy of Neurology

Psychiatric symptoms with initiation of carbidopa-levodopa treatment

JAMES T-Y. LIN, M.D. and DEWEY K. ZIEGLER, M.D.

From the Department of Neurology, University of Kansas Medical Center, College of Health Sciences and Hospital, Kansas City, Kansas.

Two patients who had had no previous psychiatric symptoms became psychotic after their antiparkinsonism medication was changed from levodopa alone to a combination of levodopa and carbidopa, despite adherence to the appropriate and recommended dosage. Psychiatric symptoms disappeared after treatment with levodopa alone was resumed.

Dr. Ziegler's address is Department of Neurology, University of Kansas Medical Center, Rainbow Blvd at 39th St., Kansas City, KS 66103.

Received for publication November 10, 1975.






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