HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Correspondence: Submit a response Alert me when this article is cited Alert me when Correspondence are posted Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by BIRD, M. T. Articles by PRENSKY, A. L. Search for Related Content PubMed PubMed Citation Articles by BIRD, M. T. Articles by PRENSKY, A. L.

A follow-up study of Sydenham's chorea

From the Edward Mallinckrodt Department of Pediatrics and the Department of Neurology and Neurosurgery (Neurology), Washington University School of Medicine, and the Division of Neurology, St. Louis Children's Hospital, St. Louis.

Twenty-five patients convalescing from Sydenham's chorea were contrasted by clinical examination, electroencephalograms, and psychometric and psychologic tests to 15 siblings and 20 matched rheumatic fever controls. A group of 10 postchoreic patients who had two or more signs could be identified. Patients in this group had all the signs classified as moderate or severe, performed less well than other choreic subjects on the Bender gestalt test, and had a higher percentage of abnormal electroencephalograms but not a higher incidence of behavioral disorders. This subgroup could not be predicted from a review of neurologic history or from analysis of the acute episode of chorea. Our data would suggest that uncomplicated Sydenham's chorea is not necessarily a benign self-limited affliction of the central nervous system and that some patients are left with definite, albeit minimal, neurologic residua.

Reprint requests should be addressed to Dr. Prensky at the Edward Mallinckrodt Department of Pediatrics, St. Louis Children's Hospital, 500 S. Kingshighway Blvd., St. Louis, MO 63110.

This work was supported in part by the Allen P. and Josephine B. Green Foundation, Mexico, Missouri, and NINDS Grant 5T01NS05633.

Presented in part at a meeting of the Child Neurology Society, Madison, Wisconsin, October 10, 1974.

Received for publication November 6, 1975.

This article has been cited by other articles:

				D. S. Reddy and M. A. Rogawski Chronic Treatment with the Neuroactive Steroid Ganaxolone in the Rat Induces Anticonvulsant Tolerance to Diazepam but Not to Itself J. Pharmacol. Exp. Ther., December 1, 2000; 295(3): 1241 - 1248. [Abstract] [Full Text]

				D. S. Reddy and M. A. Rogawski Enhanced Anticonvulsant Activity of Ganaxolone after Neurosteroid Withdrawal in a Rat Model of Catamenial Epilepsy J. Pharmacol. Exp. Ther., September 1, 2000; 294(3): 909 - 915. [Abstract] [Full Text]

				A. A. Kotby, N. El Badawy, S. El Sokkary, H. Moawad, and M. El Shawarby Antineuronal Antibodies in Rheumatic Chorea Clin. Vaccine Immunol., November 1, 1998; 5(6): 836 - 839. [Abstract] [Full Text]

				L. T. Ch'ien, A. N. Economides, and H. Lemmi Sydenham's Chorea and Seizures: Clinical and Electroencephalographic Studies Arch Neurol, June 1, 1978; 35(6): 382 - 385. [Abstract] [PDF]