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From the Department of Neurology, University of California, San Francisco, California.
An encephalopathy may occur following treatment of chronic pulmonary failure and is manifested by multifocal seizures, mild focal motor signs, and coma. The encephalopathy seems to be a multifactorial illness resulting from cerebral ischemica and hypoxia. The more important factors appear to be cerebral alkalosis, administration of aminophyline, and associated hypotension.
Dr. Faden's address is Department of Neurology, University of California, San Francisco, CA 94143.
This study was supported in part by USPHS grant NS-05101-19.
Received for publication June 13, 1975.
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