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NEUROLOGY 1976;26:326
© 1976 American Academy of Neurology

A study of congenital nystagmus

Waveforms

ROBERT D. YEE, M.D., EDWARD K. WONG, M.D., ROBERT W. BALOH, M.D. and VICENTE HONRUBIA, M.D.

From the Jules Stein Eye Institute, Department of Ophthalmology (Drs. Yee and Wong), the Department of Neurology (Dr. Baloh), and the Department of Otolaryngology (Dr. Honrubia), UCLA School of Medicine, Los Angeles, California.

Eighteen patients with congenital nystagmus were studied with the techniques of electronystagmography and computer analysis. We found several complex waveforms of congenital nystagmus in the primary position of gaze above those of jerk and pendular nystagmus as defined clinically. An etiologic classification of motor fixation defect and sensory fixation defect nystagmus based on waveforms is not justified. Ocular tracking studies demonstrate that the smooth pursuit system is operational in congenital nystagmus and substantiate the belief that the fast component of jerk nystagmus is a corrective movement generated by the saccadic system. Patients with congenital nystagmus are able to produce voluntary saccades with normal velocity-amplitude relationships.

Requests for reprints should be addressed to Robert D. Yee, M.D., National Eye Institute, National Institutes of Health, Bethesda, MD 20014.

This study was supported in part by Research Grant EY-0031 from the National Eye Institute.

Received for publication June 19, 1975.




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