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From the New York Medical College Center for Chronic Disease, Roosevelt Island, New York.
An interesting case of systemic lupus erythematosus (SLE) is presented in which the clinical onset of myelopathy strongly suggested demyelinating disease. Later, intracranial hypertension developed on two occasions. Postmortem examination showed the systemic lesions of SLE. In addition, demyelinating lesions were found in the spinal cord and the optic nerve, the neuropathologic picture of Devic's syndrome, a variant of multiple sclerosis. We question whether some of the cases showing necrotic myelopathy might have an autoimmune pathogenesis.
Reprint requests should be addressed to Dr. April, Associate Professor of Neurology, New York Medical College Center for Chronic Disease, Roosevelt Island, New York, NY 10017.
Received for publication February 27, 1976.
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