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Spontaneous pneumoventriculogram following radiation of a pituitary adenoma

Departments of Neurology, Radiology and Neurological Surgery, University of Miami School of Medicine, Miami, Florida.

Three years after radiation therapy for an intrasellar tumor, a 42-year-old housewife presented with headache, lethargy, and remarkable plain skull roentgenograms, in which dilated lateral and third ventricles were filled with air. Air apparently had entered the cranium through the sphenoid sinus and eroded sellar floor, extending directly through intrasellar remnants of the chromophobe adenoma and into the floor of the third ventricle. Frontal exploration showed an empty sella turcica and no residual tumor. She made an excellent recovery and has done well for 5 years after operative closure of the defect.

Received for publication October 26, 1974.

Requests for reprints should be addressed to Noble J. David, M.D., Chief, Neurology Service, Veterans Administration Hospital, Miami, FL 33125.

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