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"Saccadic nystagmus" in cerebellar cortical atrophy

Department of Neurology, St. Luke's Episcopal Hospital, Texas Medical Center, the Department of Neurophysiology, The Methodist Hospital, Texas Medical Center, and the Departments of Otolaryngology and Physiology, Baylor College of Medicine, Texas Medical Center, Houston, Texas.

An ocular dyskinesia designated "saccadic nystagmus" was observed in a patient with cerebellar cortical atrophy. Saccadic nystagmus is a sustained ocular dyskinesia present during visual fixation and abolished by eye closure. It is difficult to distinguish visually from either pendular or jerk nystagmus without eye movement recordings. The oscillations are horizontal and rapid and may be influenced by direction of gaze. Caloric nystagmus (eyes closed) and optokinetic nystagmus were normal in our patient. Visual fixation abolished caloric nystagmus, which was replaced by saccadic nystagmus.

This investigation was supported by USPHS grant NS-10940, and by grant HL-05435-P12 from the Cardiovascular Research and Training Center.

Received for publication January 16, 1975.

Reprint requests should be addressed to Dr. Alpert at 224 Hermann Professional Building, Houston, TX 77025.