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Department of Neurology, Abraham Lincoln School of Medicine, University of Illinois, Chicago.
Although the exact site of pathologic involvement and the pathogenesis remain uncertain, opsoclonus is an invaluable clinical sign in that it alone may herald an occult systemic malignancy. A thorough systematic evaluation should be undertaken to exclude an occult neoplasm in any patient who presents with opsoclonus unaccompanied by any other clinical sign.
Received for publication October 21, 1974.
Dr. Bellur's address is Department of Neurology, Abraham Lincoln School of Medicine, 912 South Wood Street, Chicago, IL 60612.
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